My beautiful daughter
You cannot know
How much my heart breaks
As I watch you grow
In time you’ll become
Independent and free
Always my daughter
And special to me
As you grow older
You will see
Through the eyes of a mother
Reflections of me
Past, present and future
All intertwined
My mother, your mother
All daughters you’ll find
Our reflections, not vanity
Mirrored lives we share
Always a daughter
Your mother, who cares.
Other terms: Palmar-Plantar Erythrodysesthesia; PPE
What is hand-foot syndrome?
Also called hand-foot syndrome or hand-to-foot syndrome, Palmar-Plantar Erythrodysesthesia is a side effect, which can occur with several types of chemotherapy or biologic therapy drugs used to treat cancer. For example, Capecitabine (Xeloda®), 5-Flurouracil (5FU), continuous-infusion doxorubicin, doxorubicin liposomal (Doxil®), and high-dose Interleukin-2 can cause this skin reaction for some patients. Following administration of chemotherapy, small amounts of drug leak out of very small blood vessels called capillaries in the palms of the hands and soles of the feet. Exposure of your hands and feet to heat as well as friction on your palms and soles increases the amount of drug in the capillaries and increases the amount of drug leakage. This leakage of drug results in redness, tenderness, and possibly peeling of the palms and soles. The redness, also known as palmar-plantar erythema, looks like sunburn. The areas affected can become dry and peel, with numbness or tingling developing. Hand-foot syndrome can be uncomfortable and can interfere with your ability to carry out normal activities.
Chemotherapy medicines are often given through an intravenous (IV) tube at a treatment center. Because XELODA is an oral chemotherapy pill that you swallow whole with water, you can take your medicine at home or work. This may enable you to take a more active role in your treatment.
Learn about the benefits of XELODA oral chemotherapy medication
